You or someone you love could be part of developing new therapies for Prader-Willi syndrome. Learn about Gedeon Richter's research study KITE-PWS, also known as RGH-706-003, to evaluate an experimental drug for hyperphagia in people with Prader-Willi syndrome. The oral drug RGH-706 works by blocking melanin-concentrating hormone (MCH), which is a key part in the brain’s food seeking mechanism, to help reduce appetite.
To be in the study, participants must meet the following basic criteria:
- Are at least 17 years of age
- Have a diagnosis of PWS
- Have a body weight of greater than 40 kg (88 lbs.) and less than 200 kg (450 lbs.)
- Have had a stable body weight for the past 3 months
- Have at least 1 consistent and reliable primary caregiver who can evaluate changes in the participant’s hyperphagia symptoms, mood, health, and behavior throughout the study
- Do not have uncontrolled diabetes or diabetes that requires insulin
Medical history and other criteria will also be reviewed to determine eligibility. The study lasts 5-6 months and requires about 8 study visits. The study drug, tests, examinations, and study-related medical care are provided at no cost. Reimbursement for certain study-related expenses such as travel may also be available.
Gedeon Richter also provided a list of doctors in the U.S. who can be contacted to provide more information about this clinical trial opportunity:
- CA , San Diego Rady Children's Hospital e-mail: firstname.lastname@example.org; email@example.com; phone: (858) 576-1700 ext. 221543; (858) 966-5808
- NY, New York Morgan Stanley Children's Hospital of NewYork e-mail: firstname.lastname@example.org; phone: (212) 305-5508
- NY, Mineola NYU Langone Hospital—Long Island e-mail: Jorge.Mejia-Corletto@nyulangone.org email@example.com; phone: (516) 663-351
- NY, Brooklyn Maimonides Medical Center e-mail: DEsingh@maimonidesmed.org; firstname.lastname@example.org; phone: (718) 283-8160
- OH, Cleveland University Hospitals Medical Center e-mail: email@example.com; Jirat.Chenbhanich@UHhospitals.org; phone: (216) 286-9202
- IL, Chicago Ann & Robert H. Lurie Children's Hospital of Chicago email: PKhanna@luriechildrens.org; firstname.lastname@example.org; phone: (312) 227-6090