Give the Gift of Hope this Holiday Season! Support PWSA | USA's 2025 Angel Drive. Donate Now

Give the Give of Hope this Holiday Season!

The 2025 Angel Drive (November 1 – December 31) is PWSA | USA’s largest annual fundraising campaign, dedicated to bringing hope and essential support to families and individuals impacted by Prader-Willi syndrome. This year, your gift is especially meaningful as we celebrate PWSA | USA’s 50th Anniversary.

Now more than ever, your support fuels our forward motion. We’re moving from hoping for a treatment to preparing for many therapies to target the full spectrum of challenges in PWS: behavior, metabolism, cognition, independence, and more. We’re expanding early diagnosis so that every child, regardless of race, location, or resources gets support from day one. And we’re closing the gap between what exists and what’s possible. Your gift makes this real. 

The next 50 years begin now, with us. Make your gift of hope using the form below. 

Donation Form

Thank You for Making an Impact!

WATCH: PWSA | USA's Hope in Action Video Series

Last year’s Angel Drive campaign introduced Hope in Action, a powerful video series that shares real stories of resilience, hope, and community from families impacted by Prader-Willi syndrome. Each story highlights the many ways PWSA | USA is making a difference, from school success and crisis support to advocacy and beyond, illustrating the strength of our families and the heart of our mission.

Watch the first video of our new Hope in Action season, featuring members of PWSA | USA’s Adults with PWS Advisory Board. Trevor Ryan, Conor Heybach, James Towle, and Abbott Philson share what self-advocacy means to them and why advocacy work is such an important part of their lives.

WATCH: PWSA | USA's 50th Anniversary Tribute Video

Fifty years ago, parents were told to lower their expectations and prepare for the worst. They chose a different path. From that refusal to give up, PWSA | USA was born – a lifeline…

Today, that lifeline still stands strong, supporting families from the moment of diagnosis through every stage of life. Whether it’s navigating infancy, school transitions, adulthood, or advanced care needs, PWSA | USA walks with families every step of the way. We provide trusted guidance, crisis support, resources, research advocacy, and hope.

We’ve built a national resource where none existed. And this year, as we celebrate 50 years of progress, we look not just at how far we’ve come, but how far we can still go.

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