Phone: 800-926-4797 or 941-312-0400
Your membership provides this website - Join Today!

 

Research Funding Opportunities

PWSA (USA) Funding Opportunities for Research on Prader-Willi Syndrome

Prader-Willi Syndrome Association USA (“PWSA (USA)”) is pleased to offer grant assistance for scientific researchers with an interest in improving the lives of those with Prader-Willi syndrome (PWS). PWSA (USA) is seeking to fund 2-4 projects competitively awarded and up to $50,000 per year for two years aimed at discovering and developing treatments, cures, and technologies benefiting those with Prader-Willi syndrome.

PWSA (USA) is especially interested in supporting research projects that have the potential for immediate and high impact to the PWS community. However, PWSA also seeks to balance its research funding between “basic” and “applied” research in order to seek new insights that could benefit its membership right away as well as to elucidate the causes of Prader-Willi syndrome to spur more potent and complete therapies in the future. While PWSA (USA) is open to insightful grants in any subject area, the following areas are of particular interest to our constituency at this time. Research (basic or applied) in these areas will receive the highest priority:

  • Obesity: Obesity is the number one threat to the life expectancy and quality of life of someone with PWS. The resulting medical consequences of obesity and controlling obesity combined with the extraordinary stress that these issues bring to families makes hyperphagia a central life long threat to those living with PWS.
  • Respiratory: Due to lifelong hypotonia and the complications of obesity, individuals with PWS are at risk for pulmonary issues. Sleep apnea, health risks due to upper respiratory infections, and aspiration are some of the concerns that PWSA (USA) believes are worth studying.
  • Other: Behavior/psychology, GI issues, appetite suppressors, genomics/proteomics, brain imaging and function, biomarkers for co-morbidities.

Grant Award Timing:

  • LETTER OF INTENT: May 20, 2008
  • INVITATION FOR FULL GRANT APPLICATION: June 25, 2008)
  • GRANT APPLICATION DUE: September 10, 2008
  • GRANT AWARD: November 18, 2008 FUNDING OF GRANT: As soon as all IRBs obtained and other requirements met

Letter of Intent

To begin the grant process, researchers seeking funds are asked to submit a 1-3 page “Letter of intent” summarizing the proposed project. Based on the Letters of Intent, PWSA (USA) will prioritize the projects and invite full grant applications from those most meritorious.

Letters of Intent should contain a summary of at least the following items:

  • Brief overview of proposed research design
  • Project goals and intent
  • Expected significance of the project for the PWS community
  • Primary investigators (please attach NIH style biosketch no more than 3-4 pages)
  • Investigators experience with PWS
  • Timing of the project
  • Estimated cost


Letter Of Intent Review Process

The Letters of Intent will be reviewed by at least the Scientific Advisory Board Chairperson of PWSA (USA) and the Research Committee of the Board of Directors. The primary but not exclusive focus of PWSA (USA) in evaluating the Letters of Intent and determining whether to invite a grant application are as follows:

 The ability of the Principal Investigator and the research institution to§ complete the project successfully.

 The potential for the project to provide valuable and accurate insight into§ an important topic area which would fulfill PWSA (USA) goals outlined above.

 The potential of the project to impact rapidly on the PWS community..§

 The reasonableness of the time and budget required given the scope of the§ research and its potential significance.

 The likelihood that the Project could not and would not receive funding§ from alternative sources (NIH, pharmaceuticals, foundations) without pilot data and likelihood of additional funding if the objectives of the study are successfully met.

Maximum Single Grant Allowed: $50,000 per year
Maximum Length of Grant: 2 year (the second year funding contingent on the timely receipt of the first year’s progress report and status)

PWSA (USA) funding may be used for technical support, supplies, equipment, and appropriate travel. Only minimal salary support for faculty level investigators will be provided. PWSA (USA) requests that institutions keep indirect costs at or under 8% in order to maximize the impact of these small grants. If needed, PWSA (USA) will work with the successful applicant’s institution to identify a funding mechanism that will allow the total award to support the project.

Required Letter of Intent Documentation
1) Completed 1-3 page Letter of Intent (see details above)
2) NIH style biosketch (2-3 pages) of primary investigators of the Project

PLEASE SUBMIT AN ELECTRONIC COPY TO:|
jheinemann@pwsausa.org

MGButler@CMH.edu

AND 2 SIGNED COPIES OF THE DOCUMENTS ABOVE TO:

Janalee Heinemann, Director of Research & Medical Affairs
The Prader-Willi Syndrome Association (USA)
8588 Potter Park Drive, Suite 500
Sarasota, FL 34238

 

 

 edited: 05/12/2008

Return to Home page

PWSA(USA) Disclaimer 

Membership
Payments

PWSA (USA)
Privacy Policy

PWSA (USA) Link Policy

Email PWSA(USA)

 Email Webmaster