Scientific Advisory Board Abstracts

Sheridan World Resort

Orlando, FL

July 2003

Genetics

• Regulation of Imprinting at the H19/Igf2 Locus

• Transgenic Rescue of the PWS-IC Deletion Mouse

• Divergence of the Prader-Willi Syndrome Imprinting Center

• Imprinting in Prader-Willi syndrome

• Microarray Analysis of Gene/Transcript Expression in Prader-Willi Syndrome: Deletion vs UPD

Endocrine (Growth Hormone)

• Effects of Growth Hormone Therapy on Body Composition and Motor Development in Young Children with Prader-Willi Syndrome

• Growth Hormone Deficiency in Adult Prader-Willi Syndrome Patients: Preliminary Findings from a 4-site Study of Genotropin Treatment

• Growth Hormone Secretion in Adult Patients with Prader-Willi Syndrome

• Effects of GH Therapy in Three Subjects with Prader-Willi Syndrome

• Effects of GH on Sleep Patterns in Prader-Willi Syndrome

• Growth Hormone for Prader-Willi Syndrome:  Why Did We Change the Label?

Medical

• Loss of Ndn results in deficiency of central respiratory drive in mice

• Clinical Differences Between Subjects with Prader-Willi Syndrome Type I and Type II Deletions

• Prader-Willi Syndrome: Clinical Concerns for the Orthopedic Surgeon 

Endocrine (Non-Growth Hormone)

• Octreotide Potently Suppresses Circulating Ghrelin Levels in Children With Prader-Willi Syndrome

• Polycystic Ovary Syndrome (PCOS) and Prader-Willi Syndrome (PWS)

• High Prevalence Of Altered Glucose Metabolism In Young Adults With Prader-Willi Syndrome

• Adrenarche in Prader Willi syndrome appears not related to insulin sensitivity and serum adiponectin

Psychiatry/Psychology

• The Relationship between Food Related Compulsivity, Memory, Intellectual Ability, and Body Mass Index in Prader-Willi Syndrome

• Gender Differences in Compulsive and Related Behavior Problems in Prader-Willi Syndrome

• Behavior and Emotional Problems in Prader-Willi Syndrome: Comparisons to Autism and Williams Syndrome

• Cognitive and Achievement Abilities of Individuals with Prader-Willi Syndrome versus Others with Early Morbid Obesity

• Maladaptive and compulsive behavior in Prader-Willi syndrome: New insights from older adults

July 2003